Skincare Review: Lamelle Cathepzyme 2 Home Exfoliation System

I have loudly and repeatedly professed my devotion to enzymatic exfoliators, and I’ve also loudly and repeatedly complained that there aren’t enough out there (and no, it doesn’t count if it has granules and some enzymes). I was, of course, more that happy to give another one a bash when given the opportunity.

Lamelle is another skincare range that is exclusive so skincare professionals, and they have a small-ish range of products and treatments focused on improving specific skin conditions – it’s ranges like these that made me go into skincare in the first place. Cathepzyme 2 is part of the Correctives range, and is the potent sister to the gentler Cathepzyme 1.

Lamelle Cathepzyme Home Exfoliation System
Lamelle Cathepzyme Home Exfoliation System

How it works: Very simply, the enzymes work on normalising your skin shedding processes without interfering with anything else – enzymes only work superficially (the Stratum Corneum – the very upper layer of the epidermis) so they won’t disrupt the pH of the skin or interfere with other products you’re using. Scrubs (the stuff with granules) can impair the barrier function of the delicate facial skin, and you’re bound to have an uneven result since you’re only exfoliating where the actual granule hits the skin. I’ve seen microscopic images of what your face looks like after you’ve scrubbed – there are hundreds of little cuts on the surface. It’s nasty.

Even though I was a little nervous about using Cathepzyme 2, the more potent version that’s also suitable for body ailments like Keratosis Pilaris (the nasty bumps you get on your upper arms, mostly), my skin took to it like a fish to water. Instructions say to massage the milky gel into clean, dry skin for 3 minutes and then rinse, but I find it absorbs after a minute or so (I use 2-3 pumps). I then add another pump for good measure and just leave it until the time is up. I whined because I’m used to using wet enzymatic exfoliators, but I figured it’s only 3 minutes, and I now do it right before I get in the shower (I actually rinse it off in the shower, fyi).

Cathepzyme 2 is R385 for 30ml and Lamelle products are exclusive to salons, dermatologists and aesthetic doctors. Visit their website for stockists, or phone 011 465 2264.

C xx




  1. Ursula Maritz
    Apr 21, 2018 / 10:01 AM

    Hi there
    The instructions say one pump for 3 minutes but it dries long before the 3 mins are up. How are we supposed to continue for the remainder mins?

    • Chantelle Bester
      Jan 6, 2020 / 3:58 AM

      Hi Ursula! You can either just leave it for the remainder of the time, or dampen your fingers to keep working it.

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